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Gene Information
Gene ID:4552
Symbol:MTRR
Full Name:5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Alias:MGC129643|MSR
Organism:Homo sapiens (Human)
Chromosome:5
Genetic Location:5p15.3-p15.2
Physical Location:7922216-7954236 on NC_000005.8
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:MTRR
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_002454.2NP_002445.2NC_000005.8 range: 7922216..7954236
NM_024010.2NP_076915.2NC_000005.8 range: 7922216..7954236
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005739mitochondrionCellular ComponentIEA
GO:0005829cytosolCellular ComponentTAS (9501215)
GO:0005506iron ion bindingMolecular FunctionIEA
GO:0016740transferase activityMolecular FunctionIEA
GO:0010181FMN bindingMolecular FunctionTAS (9501215)
GO:0010181FMN bindingMolecular FunctionIEA
GO:0050660FAD bindingMolecular FunctionTAS (9501215)
GO:0009055electron carrier activityMolecular FunctionIEA
GO:0050661NADP bindingMolecular FunctionTAS (9501215)
GO:0008168methyltransferase activityMolecular FunctionIEA
GO:0030586[methionine synthase] reductase activityMolecular FunctionTAS (9501215)
GO:0009086methionine biosynthetic processBiological ProcessIEA
GO:0008652amino acid biosynthetic processBiological ProcessIEA
GO:0055114oxidation reductionBiological ProcessTAS (9501215)
Other Database Cross Links
NCBI Entrez Gene:4552
HGNC:7473
Ensembl:ENSG00000124275
MIM:602568
HPRD:03979
HuGE Navigator:4552
dbSNP:MTRR
GeneCard:MTRR
AceView:MTRR