ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

MUTYH

Full Name:

mutY homolog (E. coli)

Alias:

MGC4416|MYH

Organism:

Homo sapiens (Human)

Chromosome:

1

Genetic Location:

1p34.3-p32.1

Physical Location:

45567500-45578728 on NC_000001.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

MUTYH

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001048171.1	NP_001041636.1	NC_000001.9 range: 45567500..45578728, complement
NM_001048172.1	NP_001041637.1	NC_000001.9 range: 45567500..45578728, complement
NM_001048173.1	NP_001041638.1	NC_000001.9 range: 45567500..45578728, complement
NM_001048174.1	NP_001041639.1	NC_000001.9 range: 45567500..45578728, complement
NM_012222.2	NP_036354.1	NC_000001.9 range: 45567500..45578728, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005654	nucleoplasm	Cellular Component	EXP (10583946)
GO:0005634	nucleus	Cellular Component	TAS (7823963)
GO:0019104	DNA N-glycosylase activity	Molecular Function	EXP (10583946)
GO:0032405	MutLalpha complex binding	Molecular Function	IDA (11801590)
GO:0003677	DNA binding	Molecular Function	IEA
GO:0032406	MutLbeta complex binding	Molecular Function	IDA (11801590)
GO:0032407	MutSalpha complex binding	Molecular Function	IDA (11801590)
GO:0032408	MutSbeta complex binding	Molecular Function	IDA (11801590)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0016798	hydrolase activity, acting on glycosyl bonds	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0051539	4 iron, 4 sulfur cluster binding	Molecular Function	IEA
GO:0003824	catalytic activity	Molecular Function	IEA
GO:0004519	endonuclease activity	Molecular Function	IEA
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (11801590)
GO:0006284	base-excision repair	Biological Process	IEA
GO:0045007	depurination	Biological Process	EXP (10583946)
GO:0045786	negative regulation of cell cycle	Biological Process	IEA
GO:0006298	mismatch repair	Biological Process	TAS (7823963)
GO:0008152	metabolic process	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000132781

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: