ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

4831

Symbol:

NME2

Full Name:

non-metastatic cells 2, protein (NM23B) expressed in

Alias:

MGC111212|NDPK-B|NDPKB|NM23-H2|NM23B|puf

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

17q21.3

Physical Location:

46597889-46604103 on NC_000017.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

NME2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001018137.1	NP_001018147.1	NC_000017.9 range: 46597889..46604103
NM_001018138.1	NP_001018148.1	NC_000017.9 range: 46597889..46604103
NM_001018139.1	NP_001018149.1	NC_000017.9 range: 46597889..46604103
NM_002512.2	NP_002503.1	NC_000017.9 range: 46597889..46604103

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	NAS
GO:0001726	ruffle	Cellular Component	IDA (11919189)
GO:0030027	lamellipodium	Cellular Component	IDA (11919189)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	NAS
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (17353931)
GO:0004550	nucleoside diphosphate kinase activity	Molecular Function	TAS
GO:0000287	magnesium ion binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	TAS (8392752)
GO:0004550	nucleoside diphosphate kinase activity	Molecular Function	IEA
GO:0043066	negative regulation of apoptosis	Biological Process	IMP (16862176)
GO:0045618	positive regulation of keratinocyte differentiation	Biological Process	IMP (16862176)
GO:0045682	regulation of epidermis development	Biological Process	IMP (16862176)
GO:0045786	negative regulation of cell cycle	Biological Process	IEA
GO:0009142	nucleoside triphosphate biosynthetic process	Biological Process	NAS
GO:0009117	nucleotide metabolic process	Biological Process	IEA
GO:0008285	negative regulation of cell proliferation	Biological Process	TAS
GO:0007155	cell adhesion	Biological Process	TAS (11919189)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	TAS (8392752)
GO:0006350	transcription	Biological Process	IEA
GO:0006241	CTP biosynthetic process	Biological Process	IEA
GO:0006228	UTP biosynthetic process	Biological Process	IEA
GO:0006183	GTP biosynthetic process	Biological Process	IEA
GO:0050679	positive regulation of epithelial cell proliferation	Biological Process	IMP (16862176)