ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

ACR

Full Name:

acrosin

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

22q13-qter|22q13.33

Physical Location:

49523517-49530592 on NC_000022.9

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 11434 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

ACR

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001097.2	NP_001088.2	NC_000022.9 range: 49523517..49530592

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0043234	protein complex	Cellular Component	IDA (7521127)
GO:0043159	acrosomal matrix	Cellular Component	TAS (12398221)
GO:0008233	peptidase activity	Molecular Function	IEA
GO:0008144	drug binding	Molecular Function	ISS
GO:0042806	fucose binding	Molecular Function	ISS
GO:0005537	mannose binding	Molecular Function	IDA (15950652)
GO:0005515	protein binding	Molecular Function	ISS
GO:0005515	protein binding	Molecular Function	IPI (7521127\|15950651)
GO:0005507	copper ion binding	Molecular Function	NAS (6815104)
GO:0004284	acrosin activity	Molecular Function	IDA (6802470)
GO:0004040	amidase activity	Molecular Function	ISS
GO:0003677	DNA binding	Molecular Function	NAS (1937464)
GO:0008270	zinc ion binding	Molecular Function	NAS (6815104)
GO:0007341	penetration of zona pellucida	Biological Process	IDA (10369396)
GO:0007190	activation of adenylate cyclase activity	Biological Process	IDA (3880736)
GO:0002077	acrosome matrix dispersal	Biological Process	NAS (10418103)