Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:4950
Symbol:OCLN
Full Name:occludin
Organism:Homo sapiens (Human)
Chromosome:5
Genetic Location:5q13.1
Physical Location:68823874-68885888 on NC_000005.8
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D5S647  66282906
Region:66282906-76193808
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_002538.2NP_002529.1NC_000005.8 range: 68823874..68885888
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005886plasma membraneCellular ComponentTAS (8601611)
GO:0005923tight junctionCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0030054cell junctionCellular ComponentIEA
GO:0005198structural molecule activityMolecular FunctionIEA
GO:0006461protein complex assemblyBiological ProcessTAS (10749869)
Other Database Cross Links
NCBI Entrez Gene:4950
HGNC:8104
Ensembl:ENSG00000197822
MIM:602876
HPRD:04191
HuGE Navigator:4950
dbSNP:OCLN
GeneCard:OCLN
AceView:OCLN