| Gene Information |
| Gene ID: | | 5021 |
| Symbol: | | OXTR |
| Full Name: | | oxytocin receptor |
| Alias: | | OT-R |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 3 |
| Genetic Location: | | 3p25 |
| Physical Location: | | 8767093-8786299 on NC_000003.10, complement |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
|
| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID | No. of Publications | Phenotype | |
| OXTR | 1 | Alcoholism |
| | HuGE Navigator Dataset | | Name: | | HuGE Navigator | | Method: | | Literature data mining | | Publication: | | Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008]. | | Summary: | | HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia. |
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|
| Gene Refseq Sequence Annotation |
|
| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005886 | plasma membrane | Cellular Component | TAS (10858434|10910058) | |
| GO:0005887 | integral to plasma membrane | Cellular Component | TAS (10858434) | |
| GO:0005768 | endosome | Cellular Component | NR | |
| GO:0001584 | rhodopsin-like receptor activity | Molecular Function | IEA | |
| GO:0005000 | vasopressin receptor activity | Molecular Function | IEA | |
| GO:0004990 | oxytocin receptor activity | Molecular Function | TAS (10858434) | |
| GO:0004872 | receptor activity | Molecular Function | IEA | |
| GO:0006936 | muscle contraction | Biological Process | TAS (1313946) | |
| GO:0007200 | G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) | Biological Process | NR | |
| GO:0007565 | female pregnancy | Biological Process | TAS (1313946) | |
| GO:0007595 | lactation | Biological Process | TAS (1313946) | |
|
| Other Database Cross Links |
| NCBI Entrez Gene: | | 5021 |
| HGNC: | | 8529 |
| Ensembl: | | ENSG00000180914 |
| MIM: | | 167055 |
| HPRD: | | 01328 |
| HuGE Navigator: | | 5021 |
| dbSNP: | | OXTR |
| GeneCard: | | OXTR |
| AceView: | | OXTR |
