ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PLLP

Full Name:

plasma membrane proteolipid (plasmolipin)

Alias:

PMLP|TM4SF11

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

16q13

Physical Location:

55847510-55876070 on NC_000016.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has Rat: 64364 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AI683914
Fold Change:		-1.8, -1.9
Note:		Differential Expression on the cDNA array (two fold changes are from two case groups)

Dataset Information

Name:		11141048
Method:		Microarray
Tissue:		Frontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:		RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_015993.1	NP_057077.1	NC_000016.8 range: 55847510..55876070, complement

Gene Ontology (GO) Annotation