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Gene Information
Gene ID:51301
Symbol:GCNT4
Full Name:glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
Alias:C2GNT3
Organism:Homo sapiens (Human)
Chromosome:5
Genetic Location:5q12
Physical Location:74359044-74362479 on NC_000005.8, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D5S647  66282906
Region:66282906-76193808
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_016591.1NP_057675.1NC_000005.8 range: 74359044..74362479, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0000139Golgi membraneCellular ComponentIEA
GO:0005794Golgi apparatusCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0003829beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activityMolecular FunctionIEA
GO:0008109N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activityMolecular FunctionTAS (10753916)
GO:0016757transferase activity, transferring glycosyl groupsMolecular FunctionIEA
GO:0005975carbohydrate metabolic processBiological ProcessTAS (10753916)
GO:0006493protein amino acid O-linked glycosylationBiological ProcessTAS (10753916)
Other Database Cross Links
NCBI Entrez Gene:51301
HGNC:17973
Ensembl:ENSG00000176928
MIM:
HPRD:16651
HuGE Navigator:51301
dbSNP:GCNT4
GeneCard:GCNT4
AceView:GCNT4