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Gene Information
Gene ID:51393
Symbol:TRPV2
Full Name:transient receptor potential cation channel, subfamily V, member 2
Alias:MGC12549|VRL|VRL-1|VRL1
Organism:Homo sapiens (Human)
Chromosome:17
Genetic Location:17p11.2
Physical Location:16259612-16281041 on NC_000017.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:TRPV2
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Linkage Dataset
MarkerLODP valueLocation (bp)
D17S1857  16355942
Region:14355942-18355942
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_016113.3NP_057197.2NC_000017.9 range: 16259612..16281041
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0042470melanosomeCellular ComponentIEA
GO:0005887integral to plasma membraneCellular ComponentTAS (10201375)
GO:0005886plasma membraneCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentIEA
GO:0005509calcium ion bindingMolecular FunctionIEA
GO:0005262calcium channel activityMolecular FunctionIEA
GO:0005216ion channel activityMolecular FunctionTAS (10201375)
GO:0006811ion transportBiological ProcessIEA
GO:0006816calcium ion transportBiological ProcessIEA
GO:0007600sensory perceptionBiological ProcessTAS (10201375)
Other Database Cross Links
NCBI Entrez Gene:51393
HGNC:18082
Ensembl:ENSG00000187688
MIM:606676
HPRD:05980
HuGE Navigator:51393
dbSNP:TRPV2
GeneCard:TRPV2
AceView:TRPV2