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Gene Information
Gene ID:5196
Symbol:PF4
Full Name:platelet factor 4 (chemokine (C-X-C motif) ligand 4)
Alias:CXCL4|MGC138298|SCYB4
Organism:Homo sapiens (Human)
Chromosome:4
Genetic Location:4q12-q21
Physical Location:75065659-75066540 on NC_000004.10, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:PF4
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_002619.1NP_002610.1NC_000004.10 range: 75065659..75066540, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentEXP (5789664)
GO:0005576extracellular regionCellular ComponentIC (12466273)
GO:0005576extracellular regionCellular ComponentNAS (14718574)
GO:0005615extracellular spaceCellular ComponentIEA
GO:0031093platelet alpha granule lumenCellular ComponentEXP (5789664)
GO:0008201heparin bindingMolecular FunctionIDA (9531587)
GO:0008009chemokine activityMolecular FunctionTAS (12466273)
GO:0016525negative regulation of angiogenesisBiological ProcessIDA (1688470)
GO:0019221cytokine and chemokine mediated signaling pathwayBiological ProcessIDA (12041672)
GO:0030168platelet activationBiological ProcessIDA (11685038)
GO:0030595leukocyte chemotaxisBiological ProcessIDA (6945600)
GO:0006955immune responseBiological ProcessIEA
GO:0045653negative regulation of megakaryocyte differentiationBiological ProcessIDA (2140694)
Other Database Cross Links
NCBI Entrez Gene:5196
HGNC:8861
Ensembl:ENSG00000163737
MIM:173460
HPRD:01426
HuGE Navigator:5196
dbSNP:PF4
GeneCard:PF4
AceView:PF4