ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PF4

Full Name:

platelet factor 4 (chemokine (C-X-C motif) ligand 4)

Alias:

CXCL4|MGC138298|SCYB4

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

4q12-q21

Physical Location:

75065659-75066540 on NC_000004.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

PF4

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_002619.1	NP_002610.1	NC_000004.10 range: 75065659..75066540, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	EXP (5789664)
GO:0005576	extracellular region	Cellular Component	IC (12466273)
GO:0005576	extracellular region	Cellular Component	NAS (14718574)
GO:0005615	extracellular space	Cellular Component	IEA
GO:0031093	platelet alpha granule lumen	Cellular Component	EXP (5789664)
GO:0008201	heparin binding	Molecular Function	IDA (9531587)
GO:0008009	chemokine activity	Molecular Function	TAS (12466273)
GO:0016525	negative regulation of angiogenesis	Biological Process	IDA (1688470)
GO:0019221	cytokine and chemokine mediated signaling pathway	Biological Process	IDA (12041672)
GO:0030168	platelet activation	Biological Process	IDA (11685038)
GO:0030595	leukocyte chemotaxis	Biological Process	IDA (6945600)
GO:0006955	immune response	Biological Process	IEA
GO:0045653	negative regulation of megakaryocyte differentiation	Biological Process	IDA (2140694)