ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PFAS

Full Name:

phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)

Alias:

FGAMS|FGARAT|KIAA0361|PURL

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

17p13.1

Physical Location:

8093361-8114527 on NC_000017.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

PFAS

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_012393.1	NP_036525.1	NC_000017.9 range: 8093361..8114527

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	NAS
GO:0005829	cytosol	Cellular Component	EXP (8110788)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (17353931)
GO:0004642	phosphoribosylformylglycinamidine synthase activity	Molecular Function	IEP (10548741)
GO:0004642	phosphoribosylformylglycinamidine synthase activity	Molecular Function	EXP (8110788)
GO:0016874	ligase activity	Molecular Function	IEA
GO:0006164	purine nucleotide biosynthetic process	Biological Process	IEA
GO:0006189	'de novo' IMP biosynthetic process	Biological Process	NAS (10548741)
GO:0006541	glutamine metabolic process	Biological Process	IEA