Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:5244
Symbol:ABCB4
Full Name:ATP-binding cassette, sub-family B (MDR/TAP), member 4
Alias:ABC21|GBD1|MDR2|MDR2/3|MDR3|PFIC-3|PGY3
Organism:Homo sapiens (Human)
Chromosome:7
Genetic Location:7q21.1
Physical Location:86869296-86942954 on NC_000007.12, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:ABCB4
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000443.3NP_000434.1NC_000007.12 range: 86869296..86942954, complement
NM_018849.2NP_061337.1NC_000007.12 range: 86869296..86942954, complement
NM_018850.2NP_061338.1NC_000007.12 range: 86869296..86942954, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005575cellular_componentCellular ComponentND
GO:0005624membrane fractionCellular ComponentTAS (7912658)
GO:0005887integral to plasma membraneCellular ComponentTAS (7912658)
GO:0016020membraneCellular ComponentIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0005524ATP bindingMolecular FunctionIEA
GO:0016887ATPase activityMolecular FunctionIEA
GO:0016787hydrolase activityMolecular FunctionIEA
GO:0008559xenobiotic-transporting ATPase activityMolecular FunctionIEA
GO:0009410response to xenobiotic stimulusBiological ProcessNAS (7893760)
GO:0006810transportBiological ProcessTAS (8106172)
GO:0006629lipid metabolic processBiological ProcessTAS (7912658)
GO:0042493response to drugBiological ProcessTAS (7912658)
Other Database Cross Links
NCBI Entrez Gene:5244
HGNC:45
Ensembl:ENSG00000005471
MIM:171060
HPRD:01371
HuGE Navigator:5244
dbSNP:ABCB4
GeneCard:ABCB4
AceView:ABCB4