| Gene Information |
| Gene ID: | | 5245 |
| Symbol: | | PHB |
| Full Name: | | prohibitin |
| Alias: | | PHB1 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 17 |
| Genetic Location: | | 17q21 |
| Physical Location: | | 44836418-44847240 on NC_000017.9, complement |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | | Dataset Information | | Name: | | Literature Search | | Method: | | Literature search | | Summary: | | We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0016020 | membrane | Cellular Component | IEA | |
| GO:0005887 | integral to plasma membrane | Cellular Component | IDA (15274632) | |
| GO:0005743 | mitochondrial inner membrane | Cellular Component | TAS (14500729) | |
| GO:0005739 | mitochondrion | Cellular Component | IEA | |
| GO:0005654 | nucleoplasm | Cellular Component | IDA (12466959) | |
| GO:0005634 | nucleus | Cellular Component | TAS (16130169) | |
| GO:0016564 | transcription repressor activity | Molecular Function | IDA (12566959) | |
| GO:0016563 | transcription activator activity | Molecular Function | IDA (14500729) | |
| GO:0005515 | protein binding | Molecular Function | IPI (11302691) | |
| GO:0016575 | histone deacetylation | Biological Process | IDA (12466959) | |
| GO:0016481 | negative regulation of transcription | Biological Process | IDA (12566959) | |
| GO:0008285 | negative regulation of cell proliferation | Biological Process | NAS (12466959) | |
| GO:0007165 | signal transduction | Biological Process | TAS (16130169) | |
| GO:0006260 | DNA replication | Biological Process | IEA | |
| GO:0042981 | regulation of apoptosis | Biological Process | TAS (16130169) | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 5245 |
| HGNC: | | 8912 |
| Ensembl: | | ENSG00000167085 |
| MIM: | | 176705 |
| HPRD: | | 01454 |
| HuGE Navigator: | | 5245 |
| dbSNP: | | PHB |
| GeneCard: | | PHB |
| AceView: | | PHB |
