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Gene Information
Gene ID:53421
Full Name:Sec61 alpha 1 subunit (S. cerevisiae)
Organism:Mus musculus (Mouse)
Genetic Location:6 D1
Physical Location:88453600-88468793 on NC_000072.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 29927    Symbol (Name): SEC61A1 (Sec61 alpha 1 subunit (S. cerevisiae))
Ortholog Status:The human GeneID 29927 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Sec61a1
Dataset Information
Tissue:Whole brain
Phenotype:Alcohol preference
Publication:Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
Summary:Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (|d|) and lowest Q values.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_016906.4NP_058602.1NC_000072.5 range: 88453600..88468793, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005783endoplasmic reticulumCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0015450P-P-bond-hydrolysis-driven protein transmembrane transporter activityMolecular FunctionIEA
GO:0006810transportBiological ProcessIEA
GO:0009306protein secretionBiological ProcessIEA
GO:0015031protein transportBiological ProcessIEA
GO:0065002intracellular protein transport across a membraneBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:53421