| Gene Information |
| Gene ID: | | 54106 |
| Symbol: | | TLR9 |
| Full Name: | | toll-like receptor 9 |
| Alias: | | CD289 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 3 |
| Genetic Location: | | 3p21.3 |
| Physical Location: | | 52230137-52235218 on NC_000003.10, complement |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | | Dataset Information | | Name: | | Literature Search | | Method: | | Literature search | | Summary: | | We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0016020 | membrane | Cellular Component | IEA | |
| GO:0005576 | extracellular region | Cellular Component | NAS (11130078) | |
| GO:0016021 | integral to membrane | Cellular Component | IEA | |
| GO:0010008 | endosome membrane | Cellular Component | EXP (14625308|14751759|15207506|16024789) | |
| GO:0035197 | siRNA binding | Molecular Function | IMP (15723075) | |
| GO:0004888 | transmembrane receptor activity | Molecular Function | IEA | |
| GO:0005515 | protein binding | Molecular Function | IEA | |
| GO:0007249 | I-kappaB kinase/NF-kappaB cascade | Biological Process | EXP (15276183) | |
| GO:0007165 | signal transduction | Biological Process | IEA | |
| GO:0006954 | inflammatory response | Biological Process | IEA | |
| GO:0042742 | defense response to bacterium | Biological Process | NAS (11130078) | |
| GO:0045078 | positive regulation of interferon-gamma biosynthetic process | Biological Process | IDA (16286015) | |
| GO:0045087 | innate immune response | Biological Process | IEA | |
| GO:0045356 | positive regulation of interferon-alpha biosynthetic process | Biological Process | IDA (16286015) | |
| GO:0045359 | positive regulation of interferon-beta biosynthetic process | Biological Process | IDA (16286015) | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 54106 |
| HGNC: | | 15633 |
| Ensembl: | | |
| MIM: | | 605474 |
| HPRD: | | 05685 |
| HuGE Navigator: | | 54106 |
| dbSNP: | | TLR9 |
| GeneCard: | | TLR9 |
| AceView: | | TLR9 |
