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Gene Information
Gene ID:54557
Symbol:SGTB
Full Name:small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
Alias:FLJ39002|SGT2
Organism:Homo sapiens (Human)
Chromosome:5
Genetic Location:5q12.3
Physical Location:64997510-65053696 on NC_000005.8, complement
Gene Type:protein-coding
Orthologs:This gene has Rat: 294708 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Z99387
Fold Change:1.6, 1.8
Note:Differential Expression on the cDNA array (two fold changes are from two case groups)
Dataset Information
Name:11141048
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_019072.2NP_061945.1NC_000005.8 range: 64997510..65053696, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005488bindingMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:54557
HGNC:23567
Ensembl:ENSG00000197860
MIM:
HPRD:18049
HuGE Navigator:54557
dbSNP:SGTB
GeneCard:SGTB
AceView:SGTB