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Gene Information
Gene ID:54925
Symbol:ZNF434
Full Name:zinc finger protein 434
Alias:FLJ20417|FLJ31901|MGC4179
Organism:Homo sapiens (Human)
Chromosome:16
Genetic Location:16p13.3
Physical Location:3372085-3391025 on NC_000016.8, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:H93281
Fold Change:0.67
P Value:4.00E-04
Tissue:Prefrontal cortex
Dataset Information
Name:15816859
Method:Microarray
Tissue:Prefrontal cortex and nucleus accumbens
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_017810.2NP_060280.2NC_000016.8 range: 3372085..3391025, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005622intracellularCellular ComponentIEA
GO:0005634nucleusCellular ComponentIEA
GO:0003676nucleic acid bindingMolecular FunctionIEA
GO:0003677DNA bindingMolecular FunctionIEA
GO:0003700transcription factor activityMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0006350transcriptionBiological ProcessIEA
GO:0006355regulation of transcription, DNA-dependentBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:54925
HGNC:20812
Ensembl:ENSG00000140987
MIM:
HPRD:15791
HuGE Navigator:54925
dbSNP:ZNF434
GeneCard:ZNF434
AceView:ZNF434