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Gene Information
Gene ID:55576
Symbol:STAB2
Full Name:stabilin 2
Alias:DKFZp434E0321|FEEL-2|FELE-2|FELL|FELL-2|FEX2|HARE|STAB-2
Organism:Homo sapiens (Human)
Chromosome:12
Genetic Location:12q23.3
Physical Location:102505198-102684631 on NC_000012.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D12S346  98052454
Region:98052454-102788867
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_017564.9NP_060034.9NC_000012.10 range: 102505198..102684631
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005887integral to plasma membraneCellular ComponentIDA (12077138)
GO:0009897external side of plasma membraneCellular ComponentISS
GO:0005886plasma membraneCellular ComponentIEA
GO:0015035protein disulfide oxidoreductase activityMolecular FunctionNAS (12077138)
GO:0016846carbon-sulfur lyase activityMolecular FunctionIEA
GO:0005540hyaluronic acid bindingMolecular FunctionISS
GO:0005515protein bindingMolecular FunctionNAS (12077138)
GO:0005044scavenger receptor activityMolecular FunctionIDA (12077138)
GO:0005041low-density lipoprotein receptor activityMolecular FunctionIDA (12077138)
GO:0004872receptor activityMolecular FunctionIEA
GO:0008368Gram-negative bacterial bindingMolecular FunctionIDA (11829752)
GO:0007155cell adhesionBiological ProcessNAS (12077138)
GO:0006898receptor-mediated endocytosisBiological ProcessTAS (12077138)
GO:0001525angiogenesisBiological ProcessNAS (12077138)
GO:0042742defense response to bacteriumBiological ProcessIDA (12077138)
Other Database Cross Links
NCBI Entrez Gene:55576
HGNC:18629
Ensembl:ENSG00000136011
MIM:608561
HPRD:10542
HuGE Navigator:55576
dbSNP:STAB2
GeneCard:STAB2
AceView:STAB2