ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PPP2R2D

Full Name:

protein phosphatase 2, regulatory subunit B, delta isoform

Alias:

MDS026

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

10q26.3

Physical Location:

133597949-133620043 on NC_000010.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Linkage Dataset

Marker

LOD

P value

Location (bp)

D10S1651

132582544

Region:		132582544-134299794
Phenotype:		Alcoholism phenotype along with age, gender, and P300 or constraint
Name:		15211641
Method:		Linkage
Publication:		Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:		A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0000159	protein phosphatase type 2A complex	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0008601	protein phosphatase type 2A regulator activity	Molecular Function	IEA
GO:0007165	signal transduction	Biological Process	IEA