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Gene Information
Gene ID:5621
Symbol:PRNP
Full Name:prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)
Alias:ASCR|CD230|CJD|GSS|MGC26679|PRIP|PrP|PrP27-30|PrP33-35C|PrPc|prion
Organism:Homo sapiens (Human)
Chromosome:20
Genetic Location:20p13
Physical Location:4614796-4630233 on NC_000020.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:PRNP
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000311.3NP_000302.1NC_000020.9 range: 4614796..4630233
NM_001080121.1NP_001073590.1NC_000020.9 range: 4614796..4630233
NM_001080122.1NP_001073591.1NC_000020.9 range: 4614796..4630233
NM_001080123.1NP_001073592.1NC_000020.9 range: 4614796..4630233
NM_183079.2NP_898902.1NC_000020.9 range: 4614796..4630233
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0019898extrinsic to membraneCellular ComponentTAS (16004966)
GO:0031225anchored to membraneCellular ComponentIEA
GO:0045121membrane raftCellular ComponentISS
GO:0005886plasma membraneCellular ComponentISS
GO:0005794Golgi apparatusCellular ComponentISS
GO:0005783endoplasmic reticulumCellular ComponentISS
GO:0005737cytoplasmCellular ComponentTAS (16004966)
GO:0042802identical protein bindingMolecular FunctionIPI (16286452)
GO:0005507copper ion bindingMolecular FunctionTAS (16294306)
GO:0008017microtubule bindingMolecular FunctionIDA (16004966)
GO:0008152metabolic processBiological ProcessTAS (3755672)
GO:0006979response to oxidative stressBiological ProcessISS
GO:0006878cellular copper ion homeostasisBiological ProcessNAS (16004966)
GO:0051260protein homooligomerizationBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:5621
HGNC:9449
Ensembl:ENSG00000171867
MIM:176640
HPRD:01453
HuGE Navigator:5621
dbSNP:PRNP
GeneCard:PRNP
AceView:PRNP