ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Eif3c

Full Name:

eukaryotic translation initiation factor 3, subunit C

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Physical Location:

133690424-133709879 on NC_000073.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 8663 Symbol (Name): EIF3C (eukaryotic translation initiation factor 3, subunit C)

Ortholog Status:

The human GeneID 8663 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

Eif3s8

Dataset Information

Name:		16618939
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Alcohol preference
Publication:		Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
Summary:		Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (\|d\|) and lowest Q values.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_146200.1	NP_666312.1	NC_000073.5 range: 133690424..133709879, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005852	eukaryotic translation initiation factor 3 complex	Cellular Component	ISO
GO:0003743	translation initiation factor activity	Molecular Function	ISO
GO:0043022	ribosome binding	Molecular Function	ISO
GO:0006412	translation	Biological Process	IEA
GO:0006413	translational initiation	Biological Process	ISO