ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Net1

Full Name:

neuroepithelial cell transforming gene 1

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

13 A1

Physical Location:

3881806-3917465 on NC_000079.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 10276 Symbol (Name): NET1 (neuroepithelial cell transforming gene 1)

Ortholog Status:

The human GeneID 10276 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AJ010045
Fold Change:		1.5, 1.6, NC, 1.3
Note:		4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2

Dataset Information

Name:		15002731
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Acute ethanol response
Publication:		Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed
Summary:		We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005085	guanyl-nucleotide exchange factor activity	Molecular Function	IEA
GO:0005089	Rho guanyl-nucleotide exchange factor activity	Molecular Function	IEA
GO:0007242	intracellular signaling cascade	Biological Process	IEA
GO:0035023	regulation of Rho protein signal transduction	Biological Process	IEA