ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Dusp14

Full Name:

dual specificity phosphatase 14

Alias:

1110014C10Rik|2310042C07Rik|D11Ertd395e|MKP-L|Mkp6

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 C|11 48.0 cM

Physical Location:

83861546-83881858 on NC_000077.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 11072 Symbol (Name): DUSP14 (dual specificity phosphatase 14)

Ortholog Status:

The human GeneID 11072 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

Dusp14

Dataset Information

Name:		16618939
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Alcohol preference
Publication:		Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
Summary:		Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (\|d\|) and lowest Q values.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_019819.3	NP_062793.2	NC_000077.5 range: 83861546..83881858, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0004721	phosphoprotein phosphatase activity	Molecular Function	IEA
GO:0004725	protein tyrosine phosphatase activity	Molecular Function	IEA
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0016791	phosphoric monoester hydrolase activity	Molecular Function	IEA
GO:0006470	protein amino acid dephosphorylation	Biological Process	IEA
GO:0016311	dephosphorylation	Biological Process	IEA