| Gene Information |
| Gene ID: | | 5646 |
| Symbol: | | PRSS3 |
| Full Name: | | protease, serine, 3 |
| Alias: | | MTG|PRSS4|TRY3|TRY4 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 9 |
| Genetic Location: | | 9p11.2 |
| Physical Location: | | 33785558-33789227 on NC_000009.10 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID | No. of Publications | Phenotype | |
| PRSS3 | 1 | Alcohol-Induced Disorders | | PRSS3 | 1 | Alcohol-Related Disorders |
| | HuGE Navigator Dataset | | Name: | | HuGE Navigator | | Method: | | Literature data mining | | Publication: | | Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008]. | | Summary: | | HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005576 | extracellular region | Cellular Component | IEA | |
| GO:0005615 | extracellular space | Cellular Component | IDA (6698368) | |
| GO:0004252 | serine-type endopeptidase activity | Molecular Function | IEA | |
| GO:0004295 | trypsin activity | Molecular Function | IDA (6698368|14507909) | |
| GO:0005509 | calcium ion binding | Molecular Function | IDA (6698368) | |
| GO:0005515 | protein binding | Molecular Function | IPI (6698368|14507909) | |
| GO:0008233 | peptidase activity | Molecular Function | IEA | |
| GO:0031638 | zymogen activation | Biological Process | IDA (6698368) | |
| GO:0007586 | digestion | Biological Process | TAS (6698368|14507909) | |
| GO:0006508 | proteolysis | Biological Process | NAS (8294000) | |
| GO:0006508 | proteolysis | Biological Process | IEA | |
| GO:0006508 | proteolysis | Biological Process | IDA (6698368) | |
| GO:0043542 | endothelial cell migration | Biological Process | IMP (15313892) | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 5646 |
| HGNC: | | 9486 |
| Ensembl: | | ENSG00000010438 |
| MIM: | | |
| HPRD: | | 06685 |
| HuGE Navigator: | | 5646 |
| dbSNP: | | PRSS3 |
| GeneCard: | | PRSS3 |
| AceView: | | PRSS3 |
