ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Frap1

Full Name:

FK506 binding protein 12-rapamycin associated protein 1

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 E1|4 71.0 cM

Physical Location:

147822715-147931791 on NC_000070.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2475 Symbol (Name): FRAP1 (FK506 binding protein 12-rapamycin associated protein 1)

Ortholog Status:

The human GeneID 2475 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap3q	Alcohol Preference Drinking	4	75	65-ter (cM)	4.6		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_020009.1	NP_064393.1	NC_000070.5 range: 147822715..147931791

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IDA (11707573)
GO:0016773	phosphotransferase activity, alcohol group as acceptor	Molecular Function	IEA
GO:0016772	transferase activity, transferring phosphorus-containing groups	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (16915281)
GO:0005488	binding	Molecular Function	IEA
GO:0016242	negative regulation of macroautophagy	Biological Process	IMP (16714284)
GO:0045792	negative regulation of cell size	Biological Process	ISS (16286931)
GO:0045792	negative regulation of cell size	Biological Process	IGI (15185396\|16286931)
GO:0030030	cell projection organization and biogenesis	Biological Process	ISS (16286931)
GO:0030030	cell projection organization and biogenesis	Biological Process	IMP (16286931)
GO:0018107	peptidyl-threonine phosphorylation	Biological Process	IDA (11707573)
GO:0007281	germ cell development	Biological Process	IDA (12140361)
GO:0045859	regulation of protein kinase activity	Biological Process	IGI (15185396)