ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Cacna2d2

Full Name:

calcium channel, voltage-dependent, alpha 2/delta subunit 2

Alias:

Cacna2d|a2d2|du|mKIAA0558|td|torpid

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 F1|9 60.0 cM

Physical Location:

107301942-107431388 on NC_000075.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 9254 Symbol (Name): CACNA2D2 (calcium channel, voltage-dependent, alpha 2/delta subunit 2)

Ortholog Status:

The human GeneID 9254 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact2	Alcohol Stimulated Activity	9	61	51-71 (cM)	3.6	4.30E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_020263.3	NP_064659.2	NC_000075.5 range: 107301942..107431388

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	RCA (12466851)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0005891	voltage-gated calcium channel complex	Cellular Component	IDA (11487633)
GO:0005262	calcium channel activity	Molecular Function	IEA
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0005245	voltage-gated calcium channel activity	Molecular Function	IDA (11487633)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005244	voltage-gated ion channel activity	Molecular Function	IEA
GO:0005216	ion channel activity	Molecular Function	IEA
GO:0048747	muscle fiber development	Biological Process	IMP (17320843)
GO:0040014	regulation of multicellular organism growth	Biological Process	IMP (17320843)
GO:0007528	neuromuscular junction development	Biological Process	IMP (17320843)
GO:0006816	calcium ion transport	Biological Process	IC (11487633)
GO:0006811	ion transport	Biological Process	IEA
GO:0006810	transport	Biological Process	IEA
GO:0060024	rhythmic synaptic transmission	Biological Process	IMP (16474392)