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Gene Information
Gene ID:57121
Symbol:LPAR5
Full Name:lysophosphatidic acid receptor 5
Alias:GPR92|GPR93|KPG_010|LPA5
Organism:Homo sapiens (Human)
Chromosome:12
Genetic Location:12p13.31
Physical Location:6598261-6615547 on NC_000012.10, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D12S99  5434815
Region:3434815-7434815
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_020400.4NP_065133.1NC_000012.10 range: 6598261..6615547, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016021integral to membraneCellular ComponentIEA
GO:0005575cellular_componentCellular ComponentND
GO:0005886plasma membraneCellular ComponentIEA
GO:0001584rhodopsin-like receptor activityMolecular FunctionIEA
GO:0045028purinergic nucleotide receptor activity, G-protein coupledMolecular FunctionIEA
GO:0004872receptor activityMolecular FunctionIEA
GO:0003674molecular_functionMolecular FunctionND
GO:0007186G-protein coupled receptor protein signaling pathwayBiological ProcessIEA
GO:0008150biological_processBiological ProcessND
GO:0007165signal transductionBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:57121
HGNC:13307
Ensembl:ENSG00000184574
MIM:606926
HPRD:09495
HuGE Navigator:57121
dbSNP:LPAR5
GeneCard:LPAR5
AceView:LPAR5