ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PBXIP1

Full Name:

pre-B-cell leukemia homeobox interacting protein 1

Alias:

HPIP

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

1q21.3

Physical Location:

153183179-153195190 on NC_000001.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Dataset Information

Name:		15816859
Method:		Microarray
Tissue:		Prefrontal cortex and nucleus accumbens
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:		Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_020524.2	NP_065385.2	NC_000001.9 range: 153183179..153195190, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	NAS (10825160)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005829	cytosol	Cellular Component	NAS (10825160)
GO:0005856	cytoskeleton	Cellular Component	IEA
GO:0005874	microtubule	Cellular Component	IEA
GO:0003714	transcription corepressor activity	Molecular Function	NAS (10825160)
GO:0007275	multicellular organismal development	Biological Process	NAS (10825160)
GO:0016481	negative regulation of transcription	Biological Process	NAS (10825160)
GO:0030154	cell differentiation	Biological Process	NAS (10825160)