ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PTGS1

Full Name:

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

Alias:

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

9q32-q33.3

Physical Location:

124173049-124197801 on NC_000009.10

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 19224 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

PTGS1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	ISS
GO:0005737	cytoplasm	Cellular Component	ISS
GO:0005792	microsome	Cellular Component	ISS
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Molecular Function	IEA
GO:0020037	heme binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0004666	prostaglandin-endoperoxide synthase activity	Molecular Function	TAS (9630216)
GO:0004601	peroxidase activity	Molecular Function	IEA
GO:0009053	electron donor activity	Molecular Function	IEA
GO:0008217	regulation of blood pressure	Biological Process	ISS
GO:0006979	response to oxidative stress	Biological Process	IEA
GO:0006633	fatty acid biosynthetic process	Biological Process	IEA
GO:0006629	lipid metabolic process	Biological Process	NAS (1907252)
GO:0001516	prostaglandin biosynthetic process	Biological Process	ISS