ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

MARK4

Full Name:

MAP/microtubule affinity-regulating kinase 4

Alias:

FLJ90097|KIAA1860|MARKL1|Nbla00650

Organism:

Homo sapiens (Human)

Chromosome:

19

Genetic Location:

19q13.3

Physical Location:

50446681-50500380 on NC_000019.8

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

MARK4

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_031417.2	NP_113605.2	NC_000019.8 range: 50446681..50500380

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005874	microtubule	Cellular Component	IDA (14594945)
GO:0005737	cytoplasm	Cellular Component	IDA (11326310)
GO:0005813	centrosome	Cellular Component	ISS
GO:0005815	microtubule organizing center	Cellular Component	IDA (14594945)
GO:0005813	centrosome	Cellular Component	IDA (14594945)
GO:0043005	neuron projection	Cellular Component	IDA (14594945)
GO:0043005	neuron projection	Cellular Component	ISS
GO:0000930	gamma-tubulin complex	Cellular Component	IDA (14594945)
GO:0043015	gamma-tubulin binding	Molecular Function	IDA (14594945)
GO:0043015	gamma-tubulin binding	Molecular Function	ISS
GO:0008017	microtubule binding	Molecular Function	ISS
GO:0008017	microtubule binding	Molecular Function	IDA (14594945)
GO:0050321	tau-protein kinase activity	Molecular Function	ISS
GO:0043130	ubiquitin binding	Molecular Function	NAS (14594945)
GO:0050321	tau-protein kinase activity	Molecular Function	IDA (14594945)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	NAS (15009667)
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IEA
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IDA (15009667)
GO:0004674	protein serine/threonine kinase activity	Molecular Function	NAS (11326310)
GO:0004713	protein-tyrosine kinase activity	Molecular Function	IEA
GO:0004674	protein serine/threonine kinase activity	Molecular Function	ISS
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (14594945\|14676191)
GO:0005524	ATP binding	Molecular Function	IEA
GO:0043068	positive regulation of programmed cell death	Biological Process	NAS (15009667)
GO:0001578	microtubule bundle formation	Biological Process	ISS
GO:0000086	G2/M transition of mitotic cell cycle	Biological Process	NAS (11326310)
GO:0001578	microtubule bundle formation	Biological Process	IEP (14594945)
GO:0016055	Wnt receptor signaling pathway	Biological Process	TAS (11326310)
GO:0008284	positive regulation of cell proliferation	Biological Process	IDA (12735302)
GO:0007399	nervous system development	Biological Process	ISS
GO:0007399	nervous system development	Biological Process	IDA (14594945)
GO:0006468	protein amino acid phosphorylation	Biological Process	TAS (14594945)
GO:0006468	protein amino acid phosphorylation	Biological Process	NAS (11326310)
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0000082	G1/S transition of mitotic cell cycle	Biological Process	NAS (12735302)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000007047

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: