ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

PTS

Full Name:

6-pyruvoyltetrahydropterin synthase

Alias:

PTPS

Organism:

Homo sapiens (Human)

Chromosome:

11

Genetic Location:

11q22.3-q23.3

Physical Location:

111602308-111609902 on NC_000011.8

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

PTS

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000317.2	NP_000308.1	NC_000011.8 range: 111602308..111609902

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IDA (11256614)
GO:0005739	mitochondrion	Cellular Component	IDA (11256614)
GO:0003874	6-pyruvoyltetrahydropterin synthase activity	Molecular Function	TAS (3308682)
GO:0042802	identical protein binding	Molecular Function	IPI (16169070)
GO:0016829	lyase activity	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0007417	central nervous system development	Biological Process	TAS (3308682)
GO:0006559	L-phenylalanine catabolic process	Biological Process	IEA
GO:0006520	amino acid metabolic process	Biological Process	TAS (3308682)
GO:0006729	tetrahydrobiopterin biosynthetic process	Biological Process	TAS (3308682)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000150787

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: