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Gene Information
Gene ID:5833
Symbol:PCYT2
Full Name:phosphate cytidylyltransferase 2, ethanolamine
Alias:ET
Organism:Homo sapiens (Human)
Chromosome:17
Genetic Location:17q25.3
Physical Location:77455383-77462585 on NC_000017.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D17S928  77846128
Region:75846128-78774742
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_002861.2NP_002852.1NC_000017.9 range: 77455383..77462585, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005575cellular_componentCellular ComponentND
GO:0003824catalytic activityMolecular FunctionIEA
GO:0004306ethanolamine-phosphate cytidylyltransferase activityMolecular FunctionTAS (9083101)
GO:0016740transferase activityMolecular FunctionIEA
GO:0008654phospholipid biosynthetic processBiological ProcessTAS (9083101)
GO:0009058biosynthetic processBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:5833
HGNC:8756
Ensembl:ENSG00000185813
MIM:602679
HPRD:04059
HuGE Navigator:5833
dbSNP:PCYT2
GeneCard:PCYT2
AceView:PCYT2