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Gene Information
Gene ID:5884
Symbol:RAD17
Full Name:RAD17 homolog (S. pombe)
Alias:CCYC|FLJ41520|HRAD17|R24L|RAD17SP|RAD24
Organism:Homo sapiens (Human)
Chromosome:5
Genetic Location:5q13
Physical Location:68700879-68746383 on NC_000005.8
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D5S647  66282906
Region:66282906-76193808
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_002873.1NP_002864.1NC_000005.8 range: 68700879..68746383
NM_133338.1NP_579916.1NC_000005.8 range: 68700879..68746383
NM_133339.1NP_579917.1NC_000005.8 range: 68700879..68746383
NM_133340.1NP_579918.1NC_000005.8 range: 68700879..68746383
NM_133341.1NP_579919.1NC_000005.8 range: 68700879..68746383
NM_133342.1NP_579920.1NC_000005.8 range: 68700879..68746383
NM_133343.1NP_579921.1NC_000005.8 range: 68700879..68746383
NM_133344.1NP_579922.1NC_000005.8 range: 68700879..68746383
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentTAS (9660800)
GO:0017111nucleoside-triphosphatase activityMolecular FunctionIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (10884395|15538388)
GO:0005524ATP bindingMolecular FunctionIEA
GO:0000076DNA replication checkpointBiological ProcessTAS (9660800)
GO:0008156negative regulation of DNA replicationBiological ProcessIMP (14657349)
GO:0007093mitotic cell cycle checkpointBiological ProcessIMP (15538388)
GO:0007049cell cycleBiological ProcessIEA
GO:0006281DNA repairBiological ProcessTAS (9660800)
GO:0000077DNA damage checkpointBiological ProcessIMP (15538388)
GO:0042325regulation of phosphorylationBiological ProcessIMP (14657349)
Other Database Cross Links
NCBI Entrez Gene:5884
HGNC:9807
Ensembl:ENSG00000152942
MIM:603139
HPRD:09124
HuGE Navigator:5884
dbSNP:RAD17
GeneCard:RAD17
AceView:RAD17