ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

RELA

Full Name:

v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)

Alias:

MGC131774|NFKB3

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

11q13

Physical Location:

65178392-65186950 on NC_000011.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

RELA

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_021975.2	NP_068810.2	NC_000011.8 range: 65178392..65186950, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005829	cytosol	Cellular Component	EXP (10723127)
GO:0005737	cytoplasm	Cellular Component	IDA (3140380)
GO:0005667	transcription factor complex	Cellular Component	IDA (12048232)
GO:0005654	nucleoplasm	Cellular Component	EXP (10723127)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IDA (3140380)
GO:0042802	identical protein binding	Molecular Function	IDA (9437432)
GO:0042301	phosphate binding	Molecular Function	IDA (10521409)
GO:0047485	protein N-terminus binding	Molecular Function	IPI (7739562)
GO:0051059	NF-kappaB binding	Molecular Function	IPI (8441377)
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0004871	signal transducer activity	Molecular Function	IEP (12761501)
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding	Molecular Function	IDA (3091258)
GO:0019901	protein kinase binding	Molecular Function	IPI (10521409\|15465828)
GO:0051092	activation of NF-kappaB transcription factor	Biological Process	IDA (15790681)
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	Biological Process	IEP (12761501)
GO:0019221	cytokine and chemokine mediated signaling pathway	Biological Process	IDA (15876188)
GO:0010224	response to UV-B	Biological Process	IDA (15616591)
GO:0010033	response to organic substance	Biological Process	IDA (10747850)
GO:0006968	cellular defense response	Biological Process	NAS (8717528)
GO:0006954	inflammatory response	Biological Process	IDA (12924514)
GO:0006916	anti-apoptosis	Biological Process	IDA (10747850)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0051607	defense response to virus	Biological Process	NAS (8717528)