ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

RFNG

Full Name:

RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

17q25

Physical Location:

77599066-77602938 on NC_000017.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Linkage Dataset

Marker

LOD

P value

Location (bp)

D17S928

77846128

Region:		75846128-78774742
Phenotype:		Alcoholism phenotype along with age, gender, and P300 or constraint
Name:		15211641
Method:		Linkage
Publication:		Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:		A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_002917.1	NP_002908.1	NC_000017.9 range: 77599066..77602938, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0000139	Golgi membrane	Cellular Component	IEA
GO:0005576	extracellular region	Cellular Component	NAS (10341080)
GO:0005794	Golgi apparatus	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0016757	transferase activity, transferring glycosyl groups	Molecular Function	IEA
GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	Molecular Function	IEA
GO:0003674	molecular_function	Molecular Function	ND
GO:0007399	nervous system development	Biological Process	IEA
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0030154	cell differentiation	Biological Process	IEA
GO:0009887	organ morphogenesis	Biological Process	NAS (10341080)