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Gene Information
Gene ID:60442
Symbol:Lin7c
Full Name:lin-7 homolog C (C. elegans)
Alias:Veli3
Organism:Rattus norvegicus (Rat)
Chromosome:3
Genetic Location:3q33
Physical Location:95327941-95335253 on NC_005102.2
Gene Type:protein-coding
Human Ortholog:GeneID: 55327    Symbol (Name): LIN7C (lin-7 homolog C (C. elegans))
Ortholog Status:The human GeneID 55327 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Lin7c
Fold Change:-1.51
Tissue:Accumbens
Gene Information
Original ID1:Lin7c
Fold Change:-1.27
Tissue:Amygdala
Gene Information
Original ID1:Lin7c
Fold Change:-1.31
Tissue:Caudate-putamen
Dataset Information
Name:17517326
Method:Microarray
Tissue:Nucleus accumbens, amygdala, frontal cortex, caudate-putamen, and hippocampus
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Kimpel et al. Alcohol. (2007) Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. PubMed
Summary:The objective of this study was to determine if there are innate differences in gene expression in selected CNS regions between inbred alcohol-preferring (iP) and -non-preferring (iNP) rats. Gene expression was determined in the nucleus accumbens (ACB), amygdala (AMYG), frontal cortex (FC), caudate-putamen (CPU), and hippocampus (HIPP) of alcohol-naive adult male iP and iNP rats, using Affymetrix Rat Genome U34A microarrays (n = 6/strain). Using Linear Modeling for Microarray Analysis with a false discovery rate threshold of 0.1, there were 16 genes with differential expression in the ACB, 54 in the AMYG, 8 in the FC, 24 in the CPU, and 21 in the HIPP. All the fold change are iP vs. iNP fold change.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_021851.1NP_068623.1NC_005102.2 range: 95327941..95335253
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0045211postsynaptic membraneCellular ComponentIEA
GO:0016323basolateral plasma membraneCellular ComponentIEA
GO:0019717synaptosomeCellular ComponentISS
GO:0030054cell junctionCellular ComponentIEA
GO:0045202synapseCellular ComponentIDA (10362251)
GO:0005923tight junctionCellular ComponentIEA
GO:0005911intercellular junctionCellular ComponentIDA (10362251)
GO:0005886plasma membraneCellular ComponentIEA
GO:0045202synapseCellular ComponentIEA
GO:0019717synaptosomeCellular ComponentIEA
GO:0030165PDZ domain bindingMolecular FunctionIPI (15024025)
GO:0005515protein bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionISS
GO:0007269neurotransmitter secretionBiological ProcessISS
GO:0007269neurotransmitter secretionBiological ProcessIEA
GO:0006887exocytosisBiological ProcessIEA
GO:0015031protein transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:60442
RGD:621164
Ensembl:ENSRNOG00000005131
dbSNP:Lin7c