ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

BCR

Full Name:

breakpoint cluster region

Alias:

ALL|BCR1|CML|D22S11|D22S662|FLJ16453|PHL

Organism:

Homo sapiens (Human)

Chromosome:

22

Genetic Location:

22q11|22q11.23

Physical Location:

21852551-21990223 on NC_000022.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

BCR

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_004327.3	NP_004318.3	NC_000022.9 range: 21852551..21990223
NM_021574.2	NP_067585.2	NC_000022.9 range: 21852551..21990223

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005575	cellular_component	Cellular Component	ND
GO:0016740	transferase activity	Molecular Function	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0004674	protein serine/threonine kinase activity	Molecular Function	NAS
GO:0005096	GTPase activator activity	Molecular Function	TAS (1903516)
GO:0005096	GTPase activator activity	Molecular Function	NAS
GO:0005089	Rho guanyl-nucleotide exchange factor activity	Molecular Function	IEA
GO:0005085	guanyl-nucleotide exchange factor activity	Molecular Function	IEA
GO:0004674	protein serine/threonine kinase activity	Molecular Function	TAS (1657398)
GO:0006468	protein amino acid phosphorylation	Biological Process	TAS (1657398)
GO:0007165	signal transduction	Biological Process	IEA
GO:0007242	intracellular signaling cascade	Biological Process	IEA
GO:0007242	intracellular signaling cascade	Biological Process	NAS
GO:0035023	regulation of Rho protein signal transduction	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000186716

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: