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Gene Information
Gene ID:613209
Symbol:DEFB136
Alias:DEFB135
Organism:Homo sapiens (Human)
Chromosome:8
Genetic Location:8p23.1
Physical Location:11877238-11879507 on NC_000008.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D8S550  10918926
Region:8918926-12918926
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001033017.2NP_001028189.2NC_000008.9 range: 11877238..11879507
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentIEA
GO:0042742defense response to bacteriumBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:613209
HGNC:
Ensembl:ENSG00000205883
MIM:
HPRD:
HuGE Navigator:613209
dbSNP:DEFB136
GeneCard:DEFB136
AceView:DEFB136