ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

RPL22

Full Name:

ribosomal protein L22

Alias:

EAP|HBP15|HBP15/L22

Organism:

Homo sapiens (Human)

Chromosome:

1

Genetic Location:

1p36.3-p36.2

Physical Location:

6167666-6182265 on NC_000001.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		W15194
Fold Change:		1.77
P Value:		1.00E-03
Tissue:		Prefrontal cortex

Dataset Information

Name:		15816859
Method:		Microarray
Tissue:		Prefrontal cortex and nucleus accumbens
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:		Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000983.3	NP_000974.1	NC_000001.9 range: 6167666..6182265, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005829	cytosol	Cellular Component	EXP (14567916)
GO:0005840	ribosome	Cellular Component	IEA
GO:0022625	cytosolic large ribosomal subunit	Cellular Component	TAS (8135813)
GO:0003723	RNA binding	Molecular Function	TAS (8135813)
GO:0003735	structural constituent of ribosome	Molecular Function	TAS (8135813)
GO:0008201	heparin binding	Molecular Function	IEA
GO:0006414	translational elongation	Biological Process	EXP (15189156)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000116251

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: