ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

RPN2

Full Name:

ribophorin II

Alias:

RIBIIR|RPN-II|RPNII|SWP1

Organism:

Homo sapiens (Human)

Chromosome:

20

Genetic Location:

20q12-q13.1

Physical Location:

35240887-35303439 on NC_000020.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		Y00282
Fold Change:		-1.8, -1.8
Note:		Differential Expression on the cDNA array (two fold changes are from two case groups)

Dataset Information

Name:		11141048
Method:		Microarray
Tissue:		Frontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:		RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_002951.2	NP_002942.2	NC_000020.9 range: 35240887..35303439

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0008250	oligosaccharyl transferase complex	Cellular Component	TAS (15835887)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0008250	oligosaccharyl transferase complex	Cellular Component	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (17220478\|17353931)
GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	Molecular Function	NAS (15835887)
GO:0006464	protein modification process	Biological Process	TAS (10660554)
GO:0018279	protein amino acid N-linked glycosylation via asparagine	Biological Process	IEA
GO:0018279	protein amino acid N-linked glycosylation via asparagine	Biological Process	NAS (15835887)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000118705

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: