ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

RXRA

Full Name:

retinoid X receptor, alpha

Alias:

FLJ16020|FLJ16733|MGC102720|NR2B1

Organism:

Homo sapiens (Human)

Chromosome:

9

Genetic Location:

9q34.3

Physical Location:

136358230-136472251 on NC_000009.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID	No. of Publications	Phenotype
RXRA	1	Alcoholism
RXRA	1	Alcohol-Related Disorders

HuGE Navigator Dataset

Name:		HuGE Navigator
Method:		Literature data mining
Publication:		Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:		HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_002957.3	NP_002948.1	NC_000009.10 range: 136358230..136472251

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (7990953)
GO:0005575	cellular_component	Cellular Component	ND
GO:0003674	molecular_function	Molecular Function	ND
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0016439	tRNA-pseudouridine synthase activity	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (12040021)
GO:0005496	steroid binding	Molecular Function	IEA
GO:0004886	retinoid-X receptor activity	Molecular Function	TAS (1310260)
GO:0003713	transcription coactivator activity	Molecular Function	TAS (1651173)
GO:0003700	transcription factor activity	Molecular Function	IDA (12037571)
GO:0003706	ligand-regulated transcription factor activity	Molecular Function	IDA (7990953)
GO:0003707	steroid hormone receptor activity	Molecular Function	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (12037571)
GO:0008150	biological_process	Biological Process	ND
GO:0007165	signal transduction	Biological Process	NAS (1310260)
GO:0006766	vitamin metabolic process	Biological Process	TAS (1651173)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000186350

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: