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Gene Information
Gene ID:6257
Symbol:RXRB
Full Name:retinoid X receptor, beta
Alias:DAUDI6|H-2RIIBP|MGC1831|NR2B2|RCoR-1
Organism:Homo sapiens (Human)
Chromosome:6
Genetic Location:6p21.3
Physical Location:33269342-33276409 on NC_000006.10, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:RXRB
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Information
Original IDNo. of PublicationsPhenotype
RXRB2Alcoholism
RXRB2Alcohol-Related Disorders
HuGE Navigator Dataset
Name:HuGE Navigator
Method:Literature data mining
Publication:Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_021976.3NP_068811.1NC_000006.10 range: 33269342..33276409, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIDA (7990953)
GO:0005634nucleusCellular ComponentIEA
GO:0043565sequence-specific DNA bindingMolecular FunctionIEA
GO:0016439tRNA-pseudouridine synthase activityMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0003700transcription factor activityMolecular FunctionIEA
GO:0005496steroid bindingMolecular FunctionIEA
GO:0004886retinoid-X receptor activityMolecular FunctionTAS (1662118)
GO:0003713transcription coactivator activityMolecular FunctionTAS (1662118)
GO:0003707steroid hormone receptor activityMolecular FunctionIEA
GO:0003706ligand-regulated transcription factor activityMolecular FunctionIDA (7990953)
GO:0003700transcription factor activityMolecular FunctionNAS (1662118)
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0006350transcriptionBiological ProcessIEA
GO:0006355regulation of transcription, DNA-dependentBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:6257
HGNC:10478
Ensembl:ENSG00000204231
MIM:180246
HPRD:01578
HuGE Navigator:6257
dbSNP:RXRB
GeneCard:RXRB
AceView:RXRB