ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

CFB

Full Name:

complement factor B

Alias:

BF|BFD|CFAB|FB|FBI12|GBG|H2-Bf|PBF2

Organism:

Homo sapiens (Human)

Chromosome:

6

Genetic Location:

6p21.3

Physical Location:

32021751-32027838 on NC_000006.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

CFB

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001710.5	NP_001701.2	NC_000006.10 range: 32021751..32027838

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005886	plasma membrane	Cellular Component	EXP (15199963)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005576	extracellular region	Cellular Component	EXP (279011\|3052276\|15199963)
GO:0001848	complement binding	Molecular Function	TAS (11367526)
GO:0004252	serine-type endopeptidase activity	Molecular Function	IEA
GO:0003812	alternative-complement-pathway C3/C5 convertase activity	Molecular Function	IEA
GO:0003812	alternative-complement-pathway C3/C5 convertase activity	Molecular Function	EXP (3052276)
GO:0008233	peptidase activity	Molecular Function	IEA
GO:0006508	proteolysis	Biological Process	IEA
GO:0006956	complement activation	Biological Process	IEA
GO:0006957	complement activation, alternative pathway	Biological Process	EXP (162484)
GO:0006957	complement activation, alternative pathway	Biological Process	NAS (8225386)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000204359

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: