Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:6357
Symbol:CCL13
Full Name:chemokine (C-C motif) ligand 13
Alias:CKb10|MCP-4|MGC17134|NCC-1|NCC1|SCYA13|SCYL1
Organism:Homo sapiens (Human)
Chromosome:17
Genetic Location:17q11.2
Physical Location:29707583-29709741 on NC_000017.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D17S798  28313925
Region:26313925-30313925
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_005408.2NP_005399.1NC_000017.9 range: 29707583..29709741
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0005576extracellular regionCellular ComponentIEA
GO:0005615extracellular spaceCellular ComponentTAS (9195948)
GO:0008009chemokine activityMolecular FunctionTAS (9558100)
GO:0004871signal transducer activityMolecular FunctionNAS (9558100)
GO:0004950chemokine receptor activityMolecular FunctionNR
GO:0006935chemotaxisBiological ProcessTAS (9195948)
GO:0006874cellular calcium ion homeostasisBiological ProcessTAS (9195948)
GO:0006955immune responseBiological ProcessIEA
GO:0007165signal transductionBiological ProcessTAS (9195948|9558100)
GO:0007267cell-cell signalingBiological ProcessTAS (9195948)
GO:0006954inflammatory responseBiological ProcessTAS (9195948)
Other Database Cross Links
NCBI Entrez Gene:6357
HGNC:10611
Ensembl:ENSG00000181374
MIM:601391
HPRD:03230
HuGE Navigator:6357
dbSNP:CCL13
GeneCard:CCL13
AceView:CCL13