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Gene Information
Gene ID:6406
Symbol:SEMG1
Full Name:semenogelin I
Alias:MGC14719|SEMG|SGI
Organism:Homo sapiens (Human)
Chromosome:20
Genetic Location:20q12-q13.2
Physical Location:43269087-43271822 on NC_000020.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D20S119  43082264
Region:41082264-45082264
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_003007.2NP_002998.1NC_000020.9 range: 43269087..43271822
NM_198139.1NP_937782.1NC_000020.9 range: 43269087..43271822
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentIEA
GO:0005615extracellular spaceCellular ComponentTAS (1517240)
GO:0030141secretory granuleCellular ComponentIEA
GO:0005198structural molecule activityMolecular FunctionIEA
GO:0007320inseminationBiological ProcessTAS (2912989)
GO:0019953sexual reproductionBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:6406
HGNC:10742
Ensembl:ENSG00000124233
MIM:182140
HPRD:01641
HuGE Navigator:6406
dbSNP:SEMG1
GeneCard:SEMG1
AceView:SEMG1