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Gene Information
Gene ID:64093
Symbol:SMOC1
Full Name:SPARC related modular calcium binding 1
Organism:Homo sapiens (Human)
Chromosome:14
Genetic Location:14q24.2
Physical Location:69415895-69568835 on NC_000014.7
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D14S258  69652605
Region:67652605-71652605
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001034852.1NP_001030024.1NC_000014.7 range: 69415895..69568835
NM_022137.4NP_071420.1NC_000014.7 range: 69415895..69568835
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentIEA
GO:0005604basement membraneCellular ComponentIEA
GO:0005509calcium ion bindingMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:64093
HGNC:20318
Ensembl:ENSG00000198732
MIM:608488
HPRD:12244
HuGE Navigator:64093
dbSNP:SMOC1
GeneCard:SMOC1
AceView:SMOC1