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Gene Information
Gene ID:64431
Symbol:ACTR6
Full Name:ARP6 actin-related protein 6 homolog (yeast)
Alias:ARP6|CDA12|FLJ13433|HSPC281|MSTP136|hARP6|hARPX
Organism:Homo sapiens (Human)
Chromosome:12
Genetic Location:12q23.1
Physical Location:99118704-99142331 on NC_000012.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D12S346  98052454
Region:98052454-102788867
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_022496.3NP_071941.1NC_000012.10 range: 99118704..99142331
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005856cytoskeletonCellular ComponentIEA
GO:0005198structural molecule activityMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIEA
GO:0008152metabolic processBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:64431
HGNC:24025
Ensembl:ENSG00000075089
MIM:
HPRD:12421
HuGE Navigator:64431
dbSNP:ACTR6
GeneCard:ACTR6
AceView:ACTR6