ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ireb2

Full Name:

iron responsive element binding protein 2

Alias:

D9Ertd85e|DKFZp564D1164|Irp2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 B|9 29.0 cM

Physical Location:

54711595-54757838 on NC_000075.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3658 Symbol (Name): IREB2 (iron-responsive element binding protein 2)

Ortholog Status:

The human GeneID 3658 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap5q	Alcohol Preference Drinking	9	25	10-35 (cM)	4.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_022655.2	NP_073146.1	NC_000075.5 range: 54711595..54757838

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005829	cytosol	Cellular Component	IDA (16144863)
GO:0005737	cytoplasm	Cellular Component	IDA (8262972)
GO:0005783	endoplasmic reticulum	Cellular Component	ISO
GO:0005794	Golgi apparatus	Cellular Component	ISO
GO:0016836	hydro-lyase activity	Molecular Function	RCA (12466851)
GO:0030350	iron-responsive element binding	Molecular Function	IDA (8262972\|14726953)
GO:0030371	translation repressor activity	Molecular Function	TAS (11175792)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0003723	RNA binding	Molecular Function	IEA
GO:0051536	iron-sulfur cluster binding	Molecular Function	IEA
GO:0051539	4 iron, 4 sulfur cluster binding	Molecular Function	IEA
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0006879	cellular iron ion homeostasis	Biological Process	IMP (14726953\|15831703)
GO:0050892	intestinal absorption	Biological Process	IGI (18177727)
GO:0006417	regulation of translation	Biological Process	IMP (14726953)
GO:0034101	erythrocyte homeostasis	Biological Process	IMP (15831703)
GO:0006782	protoporphyrinogen IX biosynthetic process	Biological Process	IMP (15831703)
GO:0006879	cellular iron ion homeostasis	Biological Process	IDA (11175792)
GO:0006879	cellular iron ion homeostasis	Biological Process	IGI (14726953)
GO:0010468	regulation of gene expression	Biological Process	IGI (18177727)
GO:0009791	post-embryonic development	Biological Process	IGI (18177727)
GO:0008152	metabolic process	Biological Process	RCA (12466851)