ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SHBG

Full Name:

sex hormone-binding globulin

Alias:

ABP|MGC126834|MGC138391|TEBG

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

17p13-p12

Physical Location:

7474215-7477394 on NC_000017.9

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 20415 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

SHBG

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Information

Original ID	No. of Publications	Phenotype
SHBG	1	Alcoholism

HuGE Navigator Dataset

Name:		HuGE Navigator
Method:		Literature data mining
Publication:		Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:		HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001040.2	NP_001031.2	NC_000017.9 range: 7474215..7477394

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	NAS (14718574)
GO:0005497	androgen binding	Molecular Function	TAS (2587256)
GO:0042803	protein homodimerization activity	Molecular Function	NAS
GO:0009914	hormone transport	Biological Process	NAS