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Gene Information
Gene ID:64849
Symbol:SLC13A3
Full Name:solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
Alias:NADC3|SDCT2
Organism:Homo sapiens (Human)
Chromosome:20
Genetic Location:20q12-q13.1
Physical Location:44619869-44746513 on NC_000020.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D20S119  43082264
Region:41082264-45082264
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001011554.1NP_001011554.1NC_000020.9 range: 44619869..44746513, complement
NM_022829.4NP_073740.2NC_000020.9 range: 44619869..44746513, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0005215transporter activityMolecular FunctionIEA
GO:0015293symporter activityMolecular FunctionIEA
GO:0031402sodium ion bindingMolecular FunctionIEA
GO:0006811ion transportBiological ProcessIEA
GO:0006814sodium ion transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:64849
HGNC:14430
Ensembl:ENSG00000158296
MIM:606411
HPRD:10450
HuGE Navigator:64849
dbSNP:SLC13A3
GeneCard:SLC13A3
AceView:SLC13A3